Effects of Trehazolin, a Potent Trehalase Inhibitor, on Bombyx mori and Plant Pathogenic Fungi

Abstract

The pesticidal activities of trehazolin (TRZ), a specific and potent trehalase inhibitor, are described. TRZ inhibited trehalase of Rhizoctonia solani, a plant pathogenic fungus, with an IC₅₀ value of 66nM. Spraying rice seedlings with TRZ at a concentration of l00μg/ml suppressed infection by Rhizoctonia solani. TRZ showed insecticidal activity toward silkworms by injecting 50 to 100μg.