Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Excretion from Rats of Ketone Bodies and Methylmalonic Acid in Urine Resulting from Dietary Vitamin B12 Deficiency
Shigeki ToyoshimaFumio WatanabeHisako SaidoKazutaka MiyatakeYoshihisa Nakano
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1995 Volume 59 Issue 8 Pages 1598-1599

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Abstract

Ketone bodies were assayed in the urine of ten-week-old vitamin B12-deficient rats by a high-performance liquid chromatography. The urinary excretion of ketone bodies (352.5±68.3μmol/day) as well as of methylmalonic acid was increased significantly by dietary vitamin B12 deficiency.

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