New Antimicrobial Substances against Streptomyces scabies from Rosemary (Rosmarinus officinalis L.)

Makoto TAKENAKA; Toshiro WATANABE; Kazuo SUGAHARA; Yasuo HARADA; Shigeo YOSHIDA; Fumio SUGAWARA

doi:10.1271/bbb.61.1440

Makoto TAKENAKA, Toshiro WATANABE, Kazuo SUGAHARA, Yasuo HARADA, Shigeo YOSHIDA, Fumio SUGAWARA

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Keywords: Streptomyces scabiees, Rosmarinus officinalis L, rosmic acid, rosmanol, antimicrobial substance

JOURNAL FREE ACCESS

1997 Volume 61 Issue 9 Pages 1440-1444

DOI https://doi.org/10.1271/bbb.61.1440

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Abstract

New antimicrobial substances against Streptomyces scabies, rosmic acid and rosmanol-related compounds, were isolated from leaves of rosemary (Rosmarinus officinalis L.). The active compounds were separated in pure form by a combination of gel permeation chromatography and reverse-phase HPLC. Their structures were determined by two-dimensional NMR experiments and HR-MS analyses.

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