2004 Volume 77 Issue 12 Pages 2265-2267
The Lewis acid (borontrifluoride etherate) catalyzed novel synthesis of 2,4,6-trisubstituted-6H-1,3-oxazines is described here. Also, a new route towards an environmentally benign synthesis of the title compounds has been developed using montmorillonite K-10 clay as a catalyst under microwave irradiation (MWI). The procedure replaces the Lewis acid, and the products are obtained in a high yield and shorter reaction time.
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