2011 Volume 84 Issue 11 Pages 1237-1242
New eunicellin-based diterpenoids, klysimplexins U–X (1–4), were isolated from a cultured soft coral Klyxum simplex. Their structures were elucidated by spectroscopic methods, particularly in 1D and 2D NMR experiments. The absolute configuration of 2 was determined by Mosher’s method. Compounds 1 and 2 are the first example of 4-oxygenated eunicellin-type diterpenes isolated from soft corals of this genus.
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