Bulletin of the Chemical Society of Japan
Online ISSN : 1348-0634
Print ISSN : 0009-2673
ISSN-L : 0009-2673
90th Commemorative Account:
Fluorescent Metal Nano-Clusters as Next Generation Fluorescent Probes for Cell Imaging and Drug Delivery
Kankan BhattacharyyaSaptarshi Mukherjee
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2018 Volume 91 Issue 3 Pages 447-454

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Abstract

Fluorescent metal nano-clusters with size-dependent properties have emerged as the next generation fluorophores with versatile applications. In this article, we give a brief overview on three fluorescent metal nano-clusters, (gold, silver and copper). Because of their non-toxicity and solubility in water they are highly suitable for biological systems and in particular, live cell imaging. We show that they may be used for distinguishing cancer and non-cancer cells and selective killing of cancer cells. We also discuss their effect on enzyme catalysis.

Fluorescent metal nano-clusters with size-dependent properties have emerged as the next generation fluorophores with versatile applications. In this article, we give a brief overview on three fluorescent metal nano-clusters, (gold, silver and copper). Because of their non-toxicity and solubility in water they are highly suitable for biological systems and in particular, live cell imaging. We show that they may be used for distinguishing cancer and non-cancer cells and selective killing of cancer cells. We also discuss their effect on enzyme catalysis. Fullsize Image
 
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© 2018 The Chemical Society of Japan
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