Bulletin of the Chemical Society of Japan
Online ISSN : 1348-0634
Print ISSN : 0009-2673
ISSN-L : 0009-2673
On the Hydrazinolysis of Proteins and Peptides: A Method for the Characterization of Carboxyl-terminal Amino Acids in Proteins
Shiro AkaboriKo OhnoKozo Narita
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1952 Volume 25 Issue 3 Pages 214-218

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Abstract

(1) A brief method for the characterization of carboxyl-terminal amino acids in peptides and proteins was investigated.
(2) Several new amino acid hydrazides were synthesized.
(3) Soveral di- and tri-peptides were hydrazinolyzed and identified their carboxylterminal amino acid.
(4) The method was applied to beef insulin and tyrocidin for the demonstration of its applicability.

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