1973 Volume 46 Issue 9 Pages 2795-2797
pH and conductometric titration curves of copolypeptides containing L-lysine and either L-glutamic acid or L-aspartic acid residues have provided necessary evidence to believe that in the copolypeptides the zwitterion formation is complete at the isoionic point. The amounts of acid/alkali used up at the final inflexion/break in the titration curves agreed with the analytically determined quantity of basic/acid groups in the copolypeptides. Besides, the titration curves showed additional inflexions/breaks which distinguished between the various kinds of acid/basic groups present.
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