Bulletin of the Chemical Society of Japan
Online ISSN : 1348-0634
Print ISSN : 0009-2673
ISSN-L : 0009-2673
Efficient Synthesis of a New Amino Acid, (2S,3R,4R)-4-Chloro-3-hydroxyproline
Sannamu LeeYasushi KoderaKosaku NodaHaruhiko AoyagiTetsuo KatoNobuo Izumiya
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1986 Volume 59 Issue 2 Pages 493-495

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Abstract

An unusual new amino acid, (2S,3R,4R)-4-chloro-3-hydroxyproline, was stereospecifically synthesized through a four-intermediate from Boc-3,4-dehydro-L-proline. The obtained product was stable in a mild alkaline solution.

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