1991 Volume 64 Issue 6 Pages 1835-1839
A series of new dinuclear platinum(II) complexes have been prepared from the reaction of [PtL2(OH)2] with sulfoacetic acid: [PtL2(slac)]2·3H2O, where slac=sulfoacetate dianion; L2=1,2-diaminocyclohexane (1a–1c) or 1,2-diaminoethane (2) and L=isopropylamine (3) or ammine (4). They have di-μ-carboxylato bridged dinuclear zwitterionic structures in crystals. Among them, complexes (1a–1c) show significant antitumor activities against mice ieukemia L1210.
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