2008 年 27 巻 1 号 p. 9-11
We encountered a neonate with necrotizing enterocolitis (NEC) caused by Klebsiella pneumoniae. Clinical symptoms and inflammation did not improve despite intravenous administration of antibiotics. Bifidobacterium breve enemas were performed. After beginning enema, clinical symptoms and inflammation improved within 24 hours. Probiotic enema has high potential as a new therapy for NEC.