Bioscience and Microflora
Online ISSN : 1349-8355
Print ISSN : 1342-1441
ISSN-L : 1342-1441
Platelet Responses after Stimulation with Lipopolysaccharide from Porphyromonas gingivalis
Emiko ISOGAIHiroshi ISOGAIKimiharu HIROSEHiroko MIMURAKoichi KIMURAShunji HAYASHIMasanobu HAYASHINobuhiro FUJIIYoshimi BENNO
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1997 年 16 巻 2 号 p. 79-82

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A variety of bacterial components has been known to induce platelet aggregation. Here, we report that Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) caused direct aggregation of rabbit, but not human platelets. Pg-LPS also appeared to induce chemiluminescence response (CLR) in human polymorphonuclear neutrophils (PMNs) in whole blood or in serum. Human platelet aggregation was observed only in the PMN-platelet mixture system after stimulation with Pg-LPS.

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