J-STAGE Home  >  Publications - Top  > Bibliographic Information

Biomedical Research
Vol. 33 (2012) No. 1 P 57-61

Language:

http://doi.org/10.2220/biomedres.33.57

Communications

Stress is believed to be harmful to not only mental but also physical health. However, proving a link between stress and disease is difficult. A recent study reported that an environmental enrichment reduced cancer growth via the hypothalamic-pituitary-adrenal axis and leptin. Here, we report that mice kept in a fragrant environment enriched with α-pinene show reduced melanoma growth. Tumor volume of mice under the α-pinene environment was about 40% smaller than that in the control mice. α-Pinene had no inhibitory effect on melanoma cell proliferation in vitro, suggesting that this effect was not a direct effect of α-pinene. These results suggest that the provision of a fragrant environment may be an important factor in the therapeutic approach to cancer.

Copyright © 2012 Biomedical Research Press

Article Tools

Share this Article