生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
総説
固体NMRによる絹の分子構造解明と新しい絹様材料の開発
朝倉 哲郎
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2003 年 43 巻 6 号 p. 281-286

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The solid-state structures of Bombyx mori silk fibroin before and after spinning were determined with several solid-state NMR. A repeated β-turn type II structure was proposed for the former model and a heterogeneous structure which consists of two kinds of β-sheet structure with different inter-chain arrangement and distorted β-turn for the latter. New silk-like materials with several repeated sequences selected from B. mori and Samia cynthia ricini silk fibroins, and spider dragline silk were designed and produced using genetic engineering methods. The silk-like materials containing the cell-adhesive sequence, Arg-Gly-Asp, from fibronectin were produced similarly and their high cell-adhesive abilities were observed.

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© 2003 by THE BIOPHYSICAL SOCIETY OF JAPAN
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