2017 Volume 57 Issue 2 Pages 081-084
The use of fluorescence with a wavelength over-1000-nm (OTN) in near infrared (NIR) range has attracted more and more interests of biomedical researchers since several centimeters observation depth could be achieved in the OTN-NIR, which is ten times more compared to that in visible range. The authors have developed microscopic and small animal (in vivo) imaging systems along with the OTN-NIR fluorescent imaging probes. This paper will review the development of the imaging systems together with potential fluorescent materials in the OTN-NIR range.