生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
遺伝情報を読む:スプライス信号配列の数量化分析
飯田 陽一
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ジャーナル フリー

1987 年 27 巻 6 号 p. 268-273

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The signals which direct excision of infrons from mRNA precursors in higher eukaryotes' genes are not well understood. Although a consensus sequence, CA AG/GT AG AGT, has been proposed with the 5'-splice site actual 5'-splice site sequences differ from it to a greater or lesser degree. In the present paper, nucleotide sequences were transformed into categorical data, and quantification analysis developed by Hayashi was applied to such a system. Two classes of 5'-splice site sequences and sequences other than 5'-splice site were discriminated most distinctly. This approach was useful to know those factors which characterize 5'-splice signal sequences.

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© by THE BIOPHYSICAL SOCIETY OF JAPAN
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