Seibutsu Butsuri
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
Platelet-derived Factors Regulating the Proliferation of Rat Adult Hepatocytes
Tomoyuki HARANO, Toshikazu NAKAMURA
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Keywords: livey regeneration, hepatocyte growth factor (HGF), platelet-derived growth inhibitor (PDGI) TGF-β masking protein primary cultured hepatocytes
JOURNAL FREE ACCESS

1988 Volume 28 Issue 6 Pages 300-304

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Abstract
A growth factor and two growth inhibitors for adult rat hepatocytes were purified from rat platelets. Hepatocyte growth factor (HGF) seemed to be a hepatotropic factor which has not been purified during the past 30 years. One of growth inhibitors was identical to TGF-β. The other, named PDGI-α, was a new growth inhibitor. TGF-β masking protein that may be a regulator of the activity of TGF-β was also isolated from rat and human platelets.
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© by THE BIOPHYSICAL SOCIETY OF JAPAN
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