構造からみたバクテリオロドプシンのダイナミズム
1995 年 35 巻 2 号 p. 51-56
詳細
1995 年 35 巻 2 号 p. 51-56
Baeteriorhodopsin is a protein of light-dependent proton pump present in the purple membrane of Halobacterium salinarium. The L intermediate which arises in the microsecond time range is active complex to transmit the light energy absorbed in the chromophore to the protein. The Schiff base forms strong H-bonding to Asp85 with an intervention of a strongly H-bonding water molecule. This causes distortion in the chromomere to induce the proton transfer from the Schiff base to Asp85. The subsequent protein change in the site far from the Schiff base-Asp85 region is induced at the L stage already. Several lines of evidence suggest that energy transmission in rhodopsin proceeds in a similar way to bacteriorhodopsin.
