1997 年 37 巻 4 号 p. 161-164
A pair of pyrene groups formed an excimer due to the arrangement in close proximity within a designed four-α-helix bundle structure. At the same position were incorporated a pair of flavin moieties. The oxidative activity wellworked against1-alkyldihydronicotinamide in the presence of surfactants.A porphyrin ring was also incorporated to a two-α-helix peptide. The conjugate formed a dimetic four-α-helix bundle structure with a face-to-face porphyrin arrangement. Incorporation of Fe (III) to the conjugate gave an artificial peroxidase. These pseudoproteins may evolve for artificial functions by adequate incorporation of various catalytic and photoreactive groups.