生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
機能性原子団を装置した擬タンパク質のディノボ設計
西野 憲和
著者情報
ジャーナル フリー

1997 年 37 巻 4 号 p. 161-164

詳細
抄録

A pair of pyrene groups formed an excimer due to the arrangement in close proximity within a designed four-α-helix bundle structure. At the same position were incorporated a pair of flavin moieties. The oxidative activity wellworked against1-alkyldihydronicotinamide in the presence of surfactants.A porphyrin ring was also incorporated to a two-α-helix peptide. The conjugate formed a dimetic four-α-helix bundle structure with a face-to-face porphyrin arrangement. Incorporation of Fe (III) to the conjugate gave an artificial peroxidase. These pseudoproteins may evolve for artificial functions by adequate incorporation of various catalytic and photoreactive groups.

著者関連情報
© by THE BIOPHYSICAL SOCIETY OF JAPAN
前の記事 次の記事
feedback
Top