Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
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Hypotensive Activity and Toxicology of Constituents from Bombax ceiba Stem Bark
Rubeena SaleemSyed Iqbal AhmadMohammad AhmedZareen FaiziSadia Zikr-ur-RehmanMuhammad AliShaheen Faizi
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2003 Volume 26 Issue 1 Pages 41-46

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Abstract

A novel constituent, shamimicin, 1′′′, 1′′′′′′′-bis-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,7-dihydroxy-5-O-xylopyranosyloxy-2H-1-benzopyran alongwith lupeol, which possesses potent hypotensive activity has been isolated from Bombax ceiba stem bark. BCBMM—one of the most active hypotensive fractions has revealed its adverse effects on heart, liver and kidneys of mice at the dose of 1000 mg/kg/d.

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© 2003 The Pharmaceutical Society of Japan
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