Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Notes
The Favorable Effect of Style of Zea mays L. on Streptozotocin Induced Diabetic Nephropathy
Ryuichiro SuzukiYoshihito OkadaToru Okuyama
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2005 年 28 巻 5 号 p. 919-920

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The effectivity of water extract from the style of Zea mays on diabetic nephropathy was investigated in the development of new natural medicinal resources. Streptozotocin (STZ) induced diabetic rats were used to evaluate the therapeutic effect of the style. Urinary albumin excretion and creatinine clearance were examined for diagnosis of diabetic nephropathy. From these results it was learned that the style of Z. mays prevented glomerular hyperfiltration. The present findings indicated that the water extract of the title material suppressed the progression of diabetic glomerular sclerosis in STZ-induced diabetic rat.

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© 2005 The Pharmaceutical Society of Japan
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