A Glycosidic Isoflavonoid from Viola hondoensis W. B<small>ECKER</small> et H. B<small>OISSIEU</small> (Violaceae), and Its Effect on the Expression of Matrix Metalloproteinase-1 Caused by Ultraviolet Irradiation in Cultured Human Skin Fibroblasts

Hyung In Moon; Joongku Lee; Ok Pyo Zee; Jin Ho Chung

doi:10.1248/bpb.28.1123

Notes

A Glycosidic Isoflavonoid from Viola hondoensis W. BECKER et H. BOISSIEU (Violaceae), and Its Effect on the Expression of Matrix Metalloproteinase-1 Caused by Ultraviolet Irradiation in Cultured Human Skin Fibroblasts

Hyung In Moon, Joongku Lee, Ok Pyo Zee, Jin Ho Chung

著者情報

キーワード: Viola hondoensis, tectoridin-4′-O-β-D-glucoside, matrix metalloproteinase, human skin fibroblasts

ジャーナルフリー

2005 年 28 巻 6 号 p. 1123-1125

DOI https://doi.org/10.1248/bpb.28.1123

詳細

抄録

Isolation of the ethyl acetate soluble fraction from aerial parts of Viola hondoensis W. BECKER et H. BOISSIEU yielded one major isoflavonoid glycoside, tectoridin-4′-O-β-D-glucoside. The structure of the compound was certainly determined by chemical analyses, as well as 1D- and 2D-NMR spectroscopy. The compound exhibited potent inhibitory activity against the expression of matrix metalloproteinase-1 caused by UV-irradiation in cultured human skin fibroblasts.

責任著者(Corresponding author)

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