Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
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The Anti-Helicobacter pylori Flavones in a Brazilian Plant, Hyptis fasciculata, and the Activity of Methoxyflavones
Takahiko IsobeMatsumi DoeYoshiki MorimotoKumiko NagataAyumi Ohsaki
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2006 Volume 29 Issue 5 Pages 1039-1041

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Abstract

Two known flavonoids were isolated from a tropical medicinal plant, Hyptis fasciculata (Labiatae), found in Brazil. Flavonoids were identified as cirsilineol (1) and cirsimaritin (2) by spectroscopic means and were exhibited potent antibacterial activity against Helicobacter pylori, and cirsilineol (1) had weak antibacterial activity against Escherichia coli and Salmonella enteritidis. Following up on the relationship between anti-H. pylori activity and flavonoids with methoxy groups, several methoxy flavonoids were evaluated for proliferation of H. pylori.

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© 2006 The Pharmaceutical Society of Japan
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