Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Effect of Guarana on Exercise in Normal and Epinephrine-Induced Glycogenolytic Mice
Toshihiro MIURAMaki TATARAKazumitsu NAKAMURAIkukatsu SUZUKI
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JOURNALS FREE ACCESS

1998 Volume 21 Issue 6 Pages 646-648

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Abstract

The tonic action of water Guarana extract, (Paullinia cupana MART.), was investigated in normal, exercised, and epinephrine-induced glycogenolytic mice. A water extract of Guarana (GW) (500 mg/kg) increased the blood glucose level (p<0.001) and decreased the liver glycogen contents of mice 60 min after oral maltose administration (p<0.05). GW also significantly suppressed exercise-induced hypoglycemia (60 min : p<0.05). However, GW did not affect the blood glucose in epinephrine-induced glycogenolytic and exercise mice. These findings indicate that the suppressive mechanism of hypoglycemia might be due to the promotion of glycogen resolution.

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