Biological Sciences in Space
Online ISSN : 1349-967X
Print ISSN : 0914-9201
ISSN-L : 0914-9201
Radiation-Induced Adaptive Responses and Bystander Effects
Hideki MatsumotoAkihisa TakahashiTakeo Ohnishi
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2004 Volume 18 Issue 4 Pages 247-254


A classical paradym of radiation biology asserts that all radiation effects on cells, tissues and organisms are due to the direct action of radiation. However, there has been a recent growth of interest in the indirect actions of radiation including the radiation-induced adaptive response, the bystander effect, low-dose hypersensitivity, and genomic instability, which are specific modes of stress exhibited in response to low-dose/low-dose rate radiation. This review focuses on the radiation-induced bystander effect and the adaptive response, provides a description of the two phenomena, and discusses the contribution of the former to the latter.

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© 2004 by Japanese Society for Biological Sciences in Space
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