Abstract
A quantitative analytical method for some technical and several formulations has been developed by using thin layer chromatographic separation and ultraviolet spectrophotometry. A solution of carbamate sample was applied to silica gel plate, developed with n-hexane-ethyl acetate-formic acid (80+20+1), eluted with methanol and hydrolyzed with potassium hydroxide. The corresponding phenol produced was determined by its absorbance at maximum wavelength between 290 mμ and 300 mμ. 3, 4-Dimethylphenyl N-methylcarbamate, 3-methylphenyl N-methylcarbamate, 3, 5-dimethylphenyl N-methylcarbamate and 2-sec-butylphenyl N-methylcarbamate could be determined with standard deviation of about 0.4%.
