Cerebral Blood Flow and Metabolism (Japanese journal of cerebral blood flow and metabolism)
Online ISSN : 2188-7519
Print ISSN : 0915-9401
ISSN-L : 0915-9401
Symposium 5
Analysis of intracerebral hemorrhage in users of oral antithrombotic drugs in Toyama area (Japan)
Michiya KuboNaoya KuwayamaSoshi OkamotoEmiko HoriTakashi ShibataKimiko UmemuraYukio HorieKohtaro TanakaSatoshi Kuroda
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2016 Volume 27 Issue 2 Pages 281-286

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Abstract

Oral anticoagulants and antiplatelet drugs are increasingly used for prevention and treatment of thromboembolic events. We retrospectively analyzed consecutive 892 cases of intracerebral hemorrhage (ICH) treated from 01/2009 to 03/2015 at our Stroke Center, specially focused on with or without oral antithrombotic drugs (ATD). A total of 198 patients (22.2%) with oral ATD were identified among them. Compared with cases without ATD, enlargement of ICH under intensive blood pressure management (target systolic blood pressure <140 mmHg) was found in 18.7% with ATD vs 3.2% without ATD. Regarding clinical outcomes, poor outcomes (modified Rankin Scale score [mRS]: 4-6) were found in 70.8% vs 54.3%, respectively. Stricter control of blood pressure (130/80 mmHg) is required for patients of ICH with ATD. In order to prevent inappropriate medication of ATD and to manage with stricter control of blood pressure, supporting system by regional medical network is required.

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© 2016 The Japanese Society of Cerebral Blood Flow and Metabolism
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