2016 Volume 27 Issue 2 Pages 281-286
Oral anticoagulants and antiplatelet drugs are increasingly used for prevention and treatment of thromboembolic events. We retrospectively analyzed consecutive 892 cases of intracerebral hemorrhage (ICH) treated from 01/2009 to 03/2015 at our Stroke Center, specially focused on with or without oral antithrombotic drugs (ATD). A total of 198 patients (22.2%) with oral ATD were identified among them. Compared with cases without ATD, enlargement of ICH under intensive blood pressure management (target systolic blood pressure <140 mmHg) was found in 18.7% with ATD vs 3.2% without ATD. Regarding clinical outcomes, poor outcomes (modified Rankin Scale score [mRS]: 4-6) were found in 70.8% vs 54.3%, respectively. Stricter control of blood pressure (130/80 mmHg) is required for patients of ICH with ATD. In order to prevent inappropriate medication of ATD and to manage with stricter control of blood pressure, supporting system by regional medical network is required.