1981 Volume 21 Issue 4 Pages 491-500
Among the 8,000 fetuses subjected to autopsy by the Department of Pathology, Nagasaki University from 1947 to 1972 and the Department of Geneticopathology, Research Institute for Nuclear Medicine and Biology, Hiroshima University from 1962 to the present, 5,973 cases were picked out as their familial histories, clinical records and autopsy specimens were known. Then the cases with anomalies were selected from those 5,973 cases and analized. The anomalies totaled 1,573 cases (26.3%) in all and the anomalies of urogenital and sexual organs mounted to 425 cases or 27% of the total number of anomalies. These cases have been collected at random from the various medical institutions in the community. They also include those who died right after birth and the stillborn babies sent to us to find out the causes for death. Therefore the frequency of anomalies is more or less higher, yet, they are considered to include various kinds of anomalies impartially. The associated anomalies of urogenital system mounted to 94 cases (22%) out of 425, and if seen in terms of sexuality, 264 male cases (62.1%) predominated 139 female cases (32.7%). In some cases of urogenital anomalies caused by the autosomal recessive type, the autosomal dominant type anomalies and/or the multifactorial inheritance anomalies were found in some other organs. This means that some cases of these anomalies are caused by these "multicausal" factors.