1982 年 22 巻 4 号 p. 379-382
Reproductive medicine has progressed and many clinically important problems have been resolved. However, the mechanism of fertilization, which is the most basic and fundamental phenomenon in human reproduction, has not yet been clarified. We have investigated the morphological and functional characteristics of the human oocyte in vivo and in vitro. Observations of the human oocyte at or before fertilization in vitro including ultrastructual changes will be discussed.