Abstract
In Japan, the diagnosis and treatment of influenza virus infection has advanced dramatically. Rapid diagnosis of influenza is routine in many Japanese hospitals and clinics during winter. Influenza treatment using neuraminidase inhibitors is covered by National Health Insurance, so Japan has the world's highest neuraminidase inhibitor use, requiring careful monitoring of influenza viruses resistant to neuraminidase inhibitors and side effects. Japan is expected to achieve a pandemic plan based on stockpiling of neuraminidase inhibitors.