Marked Improvement of Left Ventricular Function After Parathyroidectomy in a Hemodialysis Patient With Secondary Hyperparathyroidism and Left Ventricular Dysfunction

Michitaka Nagashima; Kazuki Hashimoto; Takuro Shinsato; Kinya Ashida; Makoto Kobayashi; Hajime Yamashita; Masato Otsuka; Takahiko Naruko; Akira Itoh; Kazuo Haze

doi:10.1253/circj.67.269

Case Report

Marked Improvement of Left Ventricular Function After Parathyroidectomy in a Hemodialysis Patient With Secondary Hyperparathyroidism and Left Ventricular Dysfunction

Michitaka Nagashima, Kazuki Hashimoto, Takuro Shinsato, Kinya Ashida, Makoto Kobayashi, Hajime Yamashita, Masato Otsuka, Takahiko Naruko, Akira Itoh, Kazuo Haze

Author information

Michitaka Nagashima
Department of Cardiology, Osaka City General Hospital
Kazuki Hashimoto
Department of Cardiology, Osaka City General Hospital
Takuro Shinsato
Department of Cardiology, Osaka City General Hospital
Kinya Ashida
Department of Cardiology, Osaka City General Hospital
Makoto Kobayashi
Department of Cardiology, Osaka City General Hospital
Hajime Yamashita
Department of Cardiology, Osaka City General Hospital
Masato Otsuka
Department of Cardiology, Osaka City General Hospital
Takahiko Naruko
Department of Cardiology, Osaka City General Hospital
Akira Itoh
Kazuo Haze

Keywords: Hemodialysis, Left ventricular dysfunction, Parathyroidectomy, Parathyroid hormone

JOURNAL FREE ACCESS

2003 Volume 67 Issue 3 Pages 269-272

DOI https://doi.org/10.1253/circj.67.269

Details

Abstract

A 52-year-old woman, a hemodialysis patient, was admitted because of exertional dyspnea. Echocardiography showed left ventricular (LV) dilatation and reduced contraction. Coronary angiography showed no fixed stenosis. She had elevated levels of parathyroid hormone (PTH) as a result of secondary hyperparathyroidism with advanced renal failure. After parathyroidectomy, marked improvement of LV function following immediate decrease of blood levels of PTH was observed. It is suggested that PTH might have a significant role in the pathogenesis of LV dysfunction and that parathyroidectomy might be effective as a therapy for heart failure in some patients with secondary hyperparathyroidism and LV dysfunction. (Circ J 2003; 67: 269 - 272)

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