Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Ischemic Heart Disease
Diabetes Mellitus as a Predictor of Retinopathy Associated With Acute Myocardial Infarction
Takuji KatayamaTakanori YasuNozomi KinoshitaAkihiro KakehashiNorifumi KuboMuneyasu SaitoShin-ichi MomomuraMasanobu Kawakami
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2009 Volume 73 Issue 7 Pages 1278-1282

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Abstract

Background: A unique transient retinopathy characterized by soft exudates around the optic disc after percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) has been reported, so in the present study the risk factors for retinopathy associated with AMI (RAMI) were investigated. Methods and Results: The study group comprised 62 patients with their first AMI who underwent successful PCI within 24 h of onset (48 men, 14 women; age 63 ±10 years). The fundus of each eye was assessed on days 3-5, and again at 4 weeks after AMI onset. New soft exudates developed in 29 patients (47%) at 4 weeks. The frequency of diabetes mellitus (DM), and the hemoglobinA1c and peak creatine kinase concentrations were higher in patients with than in those without RAMI (55% vs 21%, P=0.008; 7.0 ±2.0% vs 5.9 ±1.4%, P=0.013; and 3,428 ±2,210 IU/L vs 2,352 ±1,652 IU/L, P=0.036, respectively). Multivariate analysis identified DM as an independent predictive factor for the occurrence of RAMI (odds ratio, 6.60; 95% confidence interval, 1.68-25.90; P=0.007). Conclusions: DM might be a risk factor for RAMI. (Circ J 2009; 73: 1278-1282)

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© 2009 THE JAPANESE CIRCULATION SOCIETY
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