Article ID: CJ-25-0382
Background: Although hemodialysis (HD) is a significant risk factor for infective endocarditis (IE), risks associated with peritoneal dialysis (PD) and specific types of HD access remain underexplored.
Methods and Results: This retrospective study analyzed 215,965 patients with end-stage renal disease (ESRD) and 1,076,532 age- and sex-matched individuals without ESRD from the general population (control group). ESRD patients were grouped into those undergoing HD or PD, with the HD group further subdivided by access type: arteriovenous fistula (AVF), catheter, or graft. The incidence of IE was lower in the PD than HD group; among patients on HD, the incidence of IE was lowest for those with access via an AVF.
Conclusions: PD and AVF access lower the risk of IE among patients with ESRD. Thus, the clinical use of both should be prioritized.
