1967 年 31 巻 6 号 p. 885-894
Two familial of cardiomegaly are reported. In the first family, seven unexpected cardiacdeaths were observed. The most striking feature of these deaths occurred in three siblings with heavy consanguinity. Three siblings died around a week after a brief episode of common cold at their age of a little over ten. Autopsy finding of one of the siblings indicated scattered fibrosis mixed with hypertrophy of the heart muscle without demonstrating etiologically significant extracardiac anomaly. In the second family, six possible cardiac deaths were noted. Among these, three female siblings died quite similary to the above mentioned siblings at their age of thirty. Literal review was made, but the genetic from of transmission of the disease is thought to be non -sex-linked and not dominant type. Etiology and symptomatology of the disease are discussed.