Abstract
Our data indicate that the resistant strains isolated from Japan show cross-resistance between EM, LCM, TC, and CP. In 1975, there were a few EM-resistant strains isolated from New Zealand and Australia at a low MIC. In 1977, no EM-resistant strains were found outside of Japan. Almost all of the EM-resistant strains were type T-12 in Japan and were not typable in New Zealand and Australia. It was suggested that the serotypes of group A streptococci are related to their antibiotic resistance pattern.