JAPANESE CIRCULATION JOURNAL
Online ISSN : 1347-4839
Print ISSN : 0047-1828
ISSN-L : 0047-1828
IS CAPTOPRIL EFFECTIVE IN PRIMARY PULMONARY HYPERTENSION?
TATSUO KOKUBUYUKIO KAZATANIMAREOMI HAMADAKEISUKE MATSUZAKITAKETOSHI ITOKAZUTAKA NISHIMURATAKAAKI OCHIFUMIYOSHI DAIMONTADAFUMI JOH
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1982 Volume 46 Issue 10 Pages 1095-1097

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Abstract

Several vasodilating agents have been used for the treatment of primary pulmonary hypertension (PPH). However, no effective therapy is currently available for this distressful disease. We tried to use an angiotensin-I converting enzyme inhibitor, captopril, for one woman suffering from PPH. Her initial treatment with furosemide, digoxin and spironolactone had shown little effect. Further administration of captopril improved her clinical condition from NYHA IV to II and made it possible to treat her at our out-clinic. No adverse effect has been found. We would like to appreciate captopril as one of the effective drugs in the treatment of PPH.

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© Japanese Circulation Society
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