JAPANESE CIRCULATION JOURNAL
Online ISSN : 1347-4839
Print ISSN : 0047-1828
ISSN-L : 0047-1828
Usefulness of Taurine in Chronic Congestive Heart Failure and Its Prospective Application : CURRENT THERAPY OF INTRACTABLE HEART FAILURE
JUNICHI AZUMAAKIHIKO SAWAMURANOBUHISA AWATA
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1992 年 56 巻 1 号 p. 95-99

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We compared the effect of oral administration of taurine (3g/day) and coenzyme Q10 (CoQ<>) (30 mg/day) in 17 patients with congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy, whose ejection fraction assessed by echocardiography was less than 50%. The changes in echo-cardiographic parameters produced by 6 weeks of treatment were evaluated in a double-blind fashion. In the taurine-treated group significant treatment effect was observed on systolic left ventricular function after 6 weeks. Such an effect was not observed in the CoQ10-treated group.

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© Japanese Circulation Society
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