Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
An Efficient Method for the Hofmann Degradation of Amides by Use of Benzyltrimethylammonium Tribromide
Shoji KajigaeshiKohichi AsanoShizuo FujisakiTakaaki KakinamiTsuyoshi Okamoto
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1989 Volume 18 Issue 3 Pages 463-464

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Abstract

The reaction of amides with a calculated amount of benzyltrimethylammonium tribromide in aqueous sodium hydroxide under mild conditions gave corresponding amines in fairly good yields.

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© 1989 The Chemical Society of Japan
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