Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Preparation of Anti-Pyrenyl Antibody and Its Chiral Recognition against a Nonnatural Amino Acid Carrying Pyrenyl Group
Mitsuhiro ImaizumiMasahiko Sisido
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1994 Volume 23 Issue 1 Pages 51-52

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Abstract

Monoclonal antibody was raised against a tetrapeptide containing L-pyrenylalanine. The antibody bound the tetrapeptide as well as L-pyrenylalanine methyl ester, indicating that it recognizes the pyrenyl group. The antibody, however, did not bind D-pyrenylalanine methyl ester. This finding suggests a potentiality of monoclonal antibodies for chiral separations.

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© 1994 The Chemical Society of Japan
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