Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Tanzawaic Acids A, B, C, and D: Inhibitors of Superoxide Anion Production from Penicillium citrinum
Makoto KuramotoKaoru YamadaMayumi ShikanoKazunaga YazawaHirokazu ArimotoTomoyuki OkamuraDaisuke Uemura
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1997 Volume 26 Issue 9 Pages 885-886

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Abstract

Tanzawaic acids have been isolated from Penicillium citrinum and their structures were elucidated by spectroscopic analysis. Their relative stereochemistries were also clarified by detailed analyses of 1H–1H coupling constants and NOE data. Tanzawaic acid B (GS-1302-1) significantly inhibits superoxide anion production in human neutrophils.

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© 1997 The Chemical Society of Japan
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