Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Cytoplasmic Molecular Delivery by Hematoporphyrin Derivative-based Photodynamic Treatment Using High-intensity Pulsed Laser Irradiation
Yuuichi MiyamotoYoshiaki SuzukiTakashi MeguroMasaya Iwaki
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2004 Volume 33 Issue 3 Pages 240-241

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Abstract

Photosensitized HeLa cells receiving high-intensity pulsed laser irradiation exhibited pores on the membrane surface. We attempted to deliver FITC-labeled dextran (71.6 kDa) into the cell cytoplasm. The ratio of FITC-positive cells in photodynamic-treated HeLa cells was significantly higher than that of non-treated HeLa cells, with no loss in cell viability.

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© 2004 The Chemical Society of Japan
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