2007 Volume 36 Issue 11 Pages 1382-1383
Glaziovianin A (1) is a novel isoflavone derivative isolated from the leaves of the Brazilian tree Astelia glazioviana. Glaziovianin A (1) showed cytotoxic activity and was suggested to be an inhibitor of tubulin polymerization. We achieved the total synthesis of glaziovianin A (1) by using the Suzuki–Miyaura coupling as a key step.
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