Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Letter
Facile Surface Functionalization of Polystyrene Substrates with Biomimetic Apatite by Utilizing Serum Proteins
Mineo HashizumeAtsushi SakaiYuri SakamotoHisao MatsunoTakeshi Serizawa
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2010 Volume 39 Issue 3 Pages 220-222

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Abstract

Serum proteins such as human serum albumin and human immunoglobulin G can induce heterogeneous nucleation of hydroxyapatite (HAp) in body fluid conditions, which make it possible for them to act as mediators to deposit HAp on polystyrene (PS) surfaces when they are immobilized on PS surfaces by physical adsorption. The present system for preparation of HAp-coated PS surfaces is simple and conversion of PS chemical structures does not occur, so that it can be applicable to various polymer surfaces having protein adsorption ability.

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© 2010 The Chemical Society of Japan
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