J-STAGE Home  >  Publications - Top  > Bibliographic Information

Chemistry Letters
Vol. 43 (2014) No. 3 P 349-351

Language:

http://doi.org/10.1246/cl.131045

Letter

Solvent-mediated Tuning of the Regioselectivity of Intramolecular Diaryl Ether Formation: Total Synthesis of (+)-Aspercyclide C

Tatsuya Yoshino1), Shuji Yamashita1), Itaru Sato1) 2), Yujiro Hayashi1), Masahiro Hirama1) 2)

1) Department of Chemistry, Graduate School of Science, Tohoku University 2) Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University

Released on J-STAGE 20140305   [Advance Publication] Released 20131121
Received 20131108   Accepted 20131116

Browse "Advance Publication" version.


A concise total synthesis of the 11-membered cyclic (+)-aspercyclide C is reported. Key to success was the fine-tuning of the reaction media to realize an oxidative, macrocyclic diaryl C–O bond formation in a regioselective and direct fashion.

Copyright © 2014 The Chemical Society of Japan
Top of this Page

Article Tools

Share this Article