Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
Letter
Water Proton Relaxivity, Superoxide Dismutase-like Activity, and Cytotoxicity of a Manganese(III) Porphyrin Having Four Poly(ethylene glycol) Tails
Yutaka HitomiTomoyuki EkawaMasahito Kodera
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Volume 43 (2014) Issue 5 Pages 732-734

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Abstract

A high-molecular-weight water-soluble manganese(III) porphyrin having four poly(ethylene glycol) tails was prepared, which enhanced the T1 relaxation rate of water protons by ca. 7.5-fold compared with manganese(III)–tetra(4-sulfonatophenyl)porphyrin. The new compound also exhibited superoxide dismutase-like activity and significantly lower cytotoxicity.

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© 2014 The Chemical Society of Japan
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