Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Letter
Coloading of Magnetic Particles and an Anionic Drug into pH-sensitive Triblock Polymeric Nanocarriers
Zhiyong WangLiming YangBin ChenYuejiao YangPing YongJie Chen
Author information
JOURNALS RESTRICTED ACCESS

2016 Volume 45 Issue 6 Pages 694-696

Details
Abstract

Triblock copolymer methoxy poly(ethylene glycol)-b-poly(dimethylaminoethyl methacrylate)-b-poly(4-vinylpyridine) (MPEG-b-PDMAEMA-b-P4VP) was synthesized by atom transfer radical polymerization. It could self-assemble into micelles in aqueous solution. Superparamagnetic Fe3O4 particles were easily incorporated into the inner core due to the effect of complexation. The ionic bonding between the cationic part of PDMAEMA and anionic drug sodium fluorescein (SFS) led to a tight loading of SFS and pH-controlled release. The coloading ability of this copolymer indicates its potential application in theranostics.

Information related to the author

This article cannot obtain the latest cited-by information.

© 2016 The Chemical Society of Japan
Previous article Next article
feedback
Top