Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Letter
A Facile Route to 4-Polyfluoroarylquinolin-2(1H)-ones and 4-Polyfluoroarylcoumarins via C–H Bond Activation
Ling FangLijun XuePeng YangXiaodan LiZhiyong Wang
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2017 Volume 46 Issue 8 Pages 1223-1226

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Abstract

Palladium-catalyzed cross-coupling reaction of 4-trifloxyquinolin-2(1H)-ones or 4-chlorocoumarins with polyfluoroarenes has been successfully developed. Under mild conditions, the reactions afforded 4-polyfluoroarylquinolin-2(1H)-ones and 4-polyfluoroarylcoumarins, which feature a wide range of bioactive compounds, with good yields.

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© 2017 The Chemical Society of Japan
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