Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Letter
Synthesis of NMs-DACN: Small and Hydrophilic Click Reaction Device
Yuuya KawasakiYuki YamanakaYuki SetoKazunobu IgawaKatsuhiko Tomooka
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2019 Volume 48 Issue 5 Pages 495-497

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Abstract

Newly designed small and hydrophilic click reaction devices, NMs-4,8-diazacyclononynes (NMs-DACNs), have been efficiently synthesized by a one-pot double Nicholas approach. NMs-DACNs react with azides smoothly under copper-free conditions and show higher water solubility than that of previously developed NTs-DACNs.

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© 2019 The Chemical Society of Japan
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