Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
ENANTIOFACE-DIFFERENTIATING (ASYMMETRIC) ADDITION OF ALKYLLITHIUM TO ALDEHYDES BY USING (2S, 2′S)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)METHYL] PYRROLIDINE AS CHIRAL LIGAND
Teruaki MukaiyamaKenso SoaiSusumu Kobayashi
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1978 Volume 7 Issue 2 Pages 219-222

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Abstract

Optically active alcohols are produced in good optical yields by treating aromatic and aliphatic aldehydes with alkyllithium by using (2S, 2′S)-2-hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine as chiral ligand.

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© The Chemical Society of Japan
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