A case of cerebral embolism caused by Cardiobacterium hominis endocarditis

Abstract

A 45-year-old woman was referred to our hospital by ambulance with left-sided palsy presented at dinner. Diffusion-weighted magnetic resonance imaging (DWI) showed a somewhat high intensity area in the right frontal lobe, and brain magnetic resonance angiography (MRA) revealed right middle cerebral artery (MCA) occlusion in the M1 distal segment. Although intravenous rt-PA treatment was initiated at 2 hours and 10 minutes after onset, recanalization was not achieved. The patient was diagnosed as infectious endocarditis, because highly echogenic vegetation was observed in the non-coronary cusp of the aortic valve; furthermore, Cardiobacterium hominis was incubated in blood culture, although fever was not so high and C-reactive protein (CRP) was not elevated at the time of hospitalization. It was thought that the bacteremia and infectious endocarditis had occurred due to tooth extraction about six months previously. The diagnosis of infectious endocarditis caused by the HACEK group containing C. hominis may become difficult because the fever was not so high and inflammation was not so severe.